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PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: C 78 H 123 N 23 O 23 S 2 Weight: 1,815.1 g/mol CAS: 221231-10-3 Origin: Residues 177-191 + N-terminal tyrosine Size: 16 amino acids Structure: Intramolecular disulfide bridge PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily soluble in water

NORSE and FIRES are defined below: Epilepsia partials continua (EPC) is defined & discussed here: NORSE NORSE definitions New-onset Refractory Status Epilepticus (NORSE) : New-onset seizure with refractory status epilepticus (i.e., refractory to two medications such as benzodiazepine plus levetiracetam)

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