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PE634010: α-Man-6-phosphate-PEG3-Azide (Disodium Salt) Pack Size:25 mg C87H134N10O38 / 1928

SKU: 18157965698

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USD250.00 USD291.00

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Description

C87H134N10O38 / 1928

32 / A synthetic heparan sulfate (HS) / heparin disaccharide bearing iduronic acid (IdoA) linked to 2-N-sulfated glucosamine (GlcNS)

Fmoc-Thr(alpha-D-Man(Ac)4)-OH

C11H13D7N2O2 / 219

PE634010: α-Man-6-phosphate-PEG3-Azide (Disodium Salt) Pack Size:25 mg C87H134N10O38 / 1928C12H22N3Na2O11P 461. 27 An mannose 6 phosphate (Man6P) ligand, supplied as the disodium salt, equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound enables the construction of lysosome targeted therapeutics and research

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