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Melanocyte Stimulating Hormones (MSH) are a class of peptide hormones produced in the intermediate lobe of the pituitary gland that stimulates pigment cells (melanocytes) in the skin and hair to produce and release melanin that leads to darker skin and hair

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The intestinal-hepatic crosstalk constitutes a pivotal component of MASLD development, linking intestinal dysbiosis to hepatic inflammation and fibrosis [1]

Potential mechanisms by which peptide exposure could influence surgical outcomes include dysregulated angiogenesis contributing to hematoma formation, altered inflammatory signaling affecting early wound healing, and perturbations in collagen organization that may influence soft-tissue integrity during the critical postoperative period