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[PubMed: 8938107] 69

Histone modification is a NAD+ dependent process

Other anti-inflammatory and antioxidant dietary supplements, such as folic acid, inositol, vitamin E, omega-3 fatty acids, alpha lipoic acid, N-acetylcysteine, have shown potential adjuvant therapeutic effects by ameliorating IR, lipid profile, reducing inflammation and oxidative stress markers of PCOS (227229, 250255)