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Disruptions of the TrxR1 system, although not substantially impacting either the cellular redox balance or GSH pools, disrupts embryonic patterning, Nrf2 regulation, and other signaling-dependent processes [49]

In addition, liposomal encapsulation of methylpalmitate and gadolinium chloride demonstrated significant macrophage clearance effects by regulating the ATP levels, respectively, similar to clodronate (Yamada et al., 2003)

Confirmed in isolated aortic tissue (Hsieh et al., 2020)

Indole-3-carbinol selectively prevents chronic stress-induced depression-but not anxiety-like behaviors via suppressing pro-inflammatory cytokine production and oxido-nitrosative stress in the brain