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Meaningful fat loss indicators include measurable changes in body composition, increased energy during fasted states, and visible changes in stubborn fat areas

maintenance of 6070% weight loss after 10+ years Time investment: One-time surgery plus follow-up care Patients with BMI criteria for bariatric surgery ( (BMI 35, or BMI 30 with other diseases such as diabetes, sleep apnea, or hypertension), would receive better outcome from permanent alteration in surgery rather than several years of pharmacological treatments