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Molecules 23 , 126 (2018)

J., Schwartz, T

For patients with symptoms suggestive of gallbladder disease or known gallstones, targeted investigations may include: Liver function tests (LFTs) : To assess for biliary obstruction or hepatic dysfunction Full blood count : To identify infection or inflammation Abdominal ultrasound : To evaluate gallstone size, number, and location, plus gallbladder wall thickness and bile duct diameter Amylase or lipase : If there is any suspicion of previous pancreatitis Serum triglycerides : Particularly if pancreatitis risk assessment is indicated If imaging reveals complicated gallstone disease such as a packed gallbladder, large stones, gallbladder wall thickening, or bile duct dilatationreferral to general surgery or gastroenterology is appropriate before considering weight loss medication

Treatment decisions should be regularly reviewed to ensure ongoing clinical benefit and appropriate resource utilisation within NHS care pathways