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For B12 deficiency, a typical injection dose is 1,000 micrograms (mcg) once a week for 4 to 8 weeks, then monthly

A doctor can assess whether the diarrhea is due to the medication or if there is another underlying cause

It was also reported in DRG neurons of wild type and TRPV4 knockout mice that activation of TRPV4 by paclitaxel induced mechanical allodynia and excessive ROS production, although the allodynia and oxidative stress was partially decreased by the TRPV4 antagonist treatment (Materazzi et al., 2012) (Table 1)

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