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NEJM, 2022

FIGURE 1 3.2 FOXO4-DRI effectively improves vascular function in prematurely aging mice To further explore the role of FOXO4-DRI in aged mice, we constructed prematurely aging mouse model by administering D-galactose (200 mg/kg) intraperitoneally for 8 weeks

Because these shifts are rarely detected until after the shipment has reached its destination, proactive cold chain protection is essential for preserving both treatment efficacy and regulatory compliance