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Overexpression of SYVN1 inhibits ferroptosis in SCIRI rats and OGD/R-treated primary spinal neurons

This, in turn, further disrupts the integrity of the BBB and may lead to hemorrhagic transformation in stroke (Lakhan et al., 2013), metastatic initiation in tumors (Spronk et al., 2021), or neurodegeneration in AD (Sweeney et al., 2018)

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In the current paper, Nasca and her colleagues, in collaboration with Natalie Rasgon, M.D., Ph.D., at Stanford University, have published a translational study looking at the LAC levels in two non-overlapping patient populations