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Not only have multiple studies shown that CoolSculpting works to kill off up to 25% of fat cells in the treated area, but thousands of happy customers across America have written reviews about their experience

The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling

He R, Wang B, Cui M, Xiong Z, Lin H, Zhao L, et al