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When using oxycodone and acetaminophen tablets with CYP3A4 inhibitors or discontinuing CYP3A4 inducers in oxycodone and acetaminophen tablets-treated patients, evaluate patients at frequent intervals and consider dosage reduction of oxycodone and acetaminophen tablets until stable drug effects are achieved [see PRECAUTIONS

Cilostazol, a phosphodiesterase-3 inhibitor, exerts both vasodilatory and antiplatelet effects that may improve cerebral perfusion and reduce vasospasm 33

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